反应详情

In the presence of Raney nickel, 53.6 g of (4-benzyloxy-3-nitrophenyl)acetonitrile in 1.2 1 of methanol is hydrogenated until 12.2 1 of hydrogen has been absorbed. The crude product obtained after removing the catalyst by filtration and after evaporation is purified by chromatography on silica gel with cyclohexane/ethyl acetate (1:1), thus obtaining 36.5 g of (3-amino-4-benzyloxyphenyl)acetonitrile as an oil.

1. customhas been absorbed
2. customThe crude product obtained
3. customafter removing the catalyst
4. filtrationby filtration
5. customafter evaporation
6. customis purified by chromatography on silica gel with cyclohexane/ethyl acetate (1:1)