HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22165980, compound → HCID 22165979, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22165980 | HCID 22165980 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22165979 | HCID 22165979 | 89.1% |
Reaction Steps
In the presence of 15.0 g of Raney nickel, 12.5 g of N-[2-(3-methoxy-4-nitrophenyl)ethyl]-trifluoroacetamide is hydrogenated in 250 ml of tetrahydrofuran. The product is recrystallized from ethyl acetate/hexane, thus obtaining 10.0 g of N-[2-(4-amino-3-methoxyphenyl)ethyl]trifluoroacetamide, mp 80°-81° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-4ba80910533a43c29e8debd35d2cc0a0 |
| Source note | uspto-grants-1990_09 |