反应详情

In the presence of 15.0 g of Raney nickel, 12.5 g of N-[2-(3-methoxy-4-nitrophenyl)ethyl]-trifluoroacetamide is hydrogenated in 250 ml of tetrahydrofuran. The product is recrystallized from ethyl acetate/hexane, thus obtaining 10.0 g of N-[2-(4-amino-3-methoxyphenyl)ethyl]trifluoroacetamide, mp 80°-81° C.

1. customThe product is recrystallized from ethyl acetate/hexane