HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)-4-oxo-7-(4-pyridyl)quinoline-3-carboxamide → 1-Ethyl-4-oxo-7-(2-pyridyl)quinoline-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)-4-oxo-7-(4-pyridyl)quinoline-3-carboxamide | HCID 443370 | — |
| Reactant | 1-Ethyl-1,4-dihydro-4-oxo-7-(2-pyridinyl)-3-quinolinecarboxylic acid | HCID 10334624 | — |
| Product | 1-Ethyl-4-oxo-7-(2-pyridyl)quinoline-3-carboxamide | HCID 478719 | — |
Reaction Steps
[I; R=H, R1C2H5, R2H, R6H, R7 -pyridinyl] was prepared from 2.94 g 1-ethyl-1,4-dihydro-4-oxo-7-(2-pyridinyl)-3-quinolinecarboxylic acid (U.S. Pat No. 3,753,993) according to the procedure of Example 1, part (h), and was obtained (2.66 g) in the form of a light-tan solid, m.p. 245°-246° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04959363 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-5f7d5b650d20457d980bf53c2eb6b3ba |
| Source note | uspto-grants-1990_09 |