Ethanol → HCID 14851929, compound

Participants

Reaction Steps

This compound was prepared by reacting rac-4-(2-chloro-phenyl)-2-iodo-6,9-dimethyl-6H-thieno-[3,2-f][1,2,4]triazolo[4,3a][4,1]diazepine (from example 108) with 5-(2-propynyl)-6(5H) phenanthridinone under the conditions described in example 37. The product was isolated by chromatography over the 50 -fold amount of silica gel using 5% (v/v) of ethanol in methylene chloride. The product was crystallized from ethanol to give yellowish crystals of the title compound with mp, 182°-186° with foaming. These crystals contained according to analytical data molar amounts of water.

Provenance & Evidence