Pyridine → Octadecylamine
Reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:7]1([CH3:14])[C:8]([CH3:13])=[CH:9][CH:10]=[CH:11][CH:12]=1>>[CH2:6]([NH2:1])[CH2:5][CH2:4][CH2:3][CH2:2][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:13][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:7][CH3:14]Participants
3
Reactant 2
Product 1
Procedure
A mixture of 39.4 g of the solid obtained in Intermediate Preparatory Example 5, 26.9 g of n-octadecylamine, 1.5 g of pyridine, and 100 g of xylene was stirred at a temperature of 120° C. for 5 hours. After cooling, the mixture was charged to 1.0 liter of methanol over 15 min with stirring and the stirring was continued for a further 1 hour. The deposited solid was collected by filtering and dried under reduced pressure, to obtain 57 g of a pale whitish yellow solid.
Sources & evidence
- ORD record
- ord-336df59734e943c7af950a7f1abaa481
- Source dataset
- uspto-grants-1994_05
- Patent number
- US05308730
Reaction notes
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