反应详情

0.3 g (1.0 mmol) 6-Bromo-4-hydroxypyrido[2,3-f]quinoxaline2, 3(1H.4H)-dione in 20 ml dimethylformamide was hydrogenated at atm. pressure by using 300 mg Pd/c (5%) as a catalyst. The reaction mixture was filtered and the filtrate was evaporated in vacuo. The residue was stirred with ethanol and the precipitate was filtered off to give 0.2 g (90%) of 4-hydroxypyrido[2,3-f]quinoxaline-2,3(1H,4H)dione. M.p. decomp. MS m/z: 229 (M+, 25%), 212 (100%), 185 (45%).

1. filtrationThe reaction mixture was filtered
2. customthe filtrate was evaporated in vacuo
3. filtrationthe precipitate was filtered off