Furfurylamine → HCID 17171359, compound

HRID 1033040Notes

Reaction equation

HRID 1033040 reaction equation
[CH3:1][N:2]=[C:3]=[O:4].[O:5]1[CH:9]=[CH:8][CH:7]=[C:6]1[CH2:10][NH2:11]>CO>[O:5]1[CH:9]=[CH:8][CH:7]=[C:6]1[CH2:10][NH:11][C:3]([NH:2][CH3:1])=[O:4]

Participants

4

Reactant 2

HCID 3438FurfurylamineHCID 12228Methyl Isocyanate

Product 1

HCID 17171359HCID 17171359, compoundYield 89.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

A solution of methyl isocyanate (34.0 g) in methanol (30 ml) was added dropwise to a solution of furan-2-ylmethylamine (57.9 g) in methanol (300 ml) at 5° to 15° C. After being stirred at room temperature for three hours, the solvent was evaporated in vacuo. The residue was treated with diisopropyl ether (400 ml) to give N-(furan-2-ylmethyl)-N'-methylurea (81.9 g).

Workup

  1. customthe solvent was evaporated in vacuo
  2. additionThe residue was treated with diisopropyl ether (400 ml)

Sources & evidence

ORD record
ord-8134f5d5d73041f29f0094d9ab472ba5
Source dataset
uspto-grants-1994_05
Patent number
US05308857

Reaction notes

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