Methyl iodide → HCID 86747809, compound

Participants

Reaction Steps

A mixture of 4-(5-cyanomethylfuran-2-yl)-2-thioureidothiazole (11.4 g) and methyl iodide (2.7 ml) in methanol (110 ml) and tetrahydrofuran (60 ml) was refluxed for 1.5 hours under stirring. Evaporation of the solvent gave a residue, which was triturated with ethyl acetate to give 2-[(amino)(methylthio)methyleneamino]-4-(5-cyanomethylfuran-2-yl)thiazole hydriodide (14.50 g).

Provenance & Evidence