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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1033052Generated: October 31, 2026

Sodium Hydroxide → HCID 10357226, compound

https://huagongshe.com/reaction/1033052

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 10363611HCID 10363611—
SolventMethanolHCID 887—
ProductHCID 10357226HCID 1035722673.1%

Reaction Conditions

Temperature60 °C

Reaction Steps

A suspension of 2-(diaminomethyleneamino)-4-[5-{3-(benzoyl)thioureido}methylfuran-2-yl]thiazole (3.20 g) and sodium hydroxide (0.32 g) in methanol (30 ml) was stirred at 60° C. for one hour. The reaction mixture was cooled in an ice bath and the resulting precipitate was collected by filtration and washed with methanol to afford 2-(diaminomethyleneamino)-4-(5-thioureidomethylfuran-2-yl)thiazole (1.73 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05308857
Source datasetuspto-grants-1994_05
ORD IDord-ba87d4c5274049688b601b5efe5265f9
Source noteuspto-grants-1994_05