Hydrochloric Acid → HCID 67819976, compound

Participants

Reaction Steps

A solution of 4N-hydrogenchloride in 1,4-dioxane (2.2 ml) was added to a mixture of 4-[5-(2-amino-2-aminosulfonyliminoethyl)furan-2-yl]-2-(diaminomethyleneamino)thiazole (3.0 g) in methanol (60 ml) and the mixture was stirred at ambient temeprature for 4 hours. To a mixture was added a diisopropyl ether (30 ml) and the isolated precipitate was collected by filtration. The precipitate was recrystallized from an aqueous ethanol to give 4-[5-(2-amino-2-aminosulfonyliminoethyl)furan-2-yl]-2-(diaminomethyleneamino)thiazole hydrochloride (2.17 g).

Provenance & Evidence