Hydrochloric Acid → HCID 19086279, compound

Participants

Reaction Steps

To a mixture of 2-(diaminomethyleneamino)-4-(5-ureidomethylfuran-2-yl)thiazole (15.4 g) in methanol (160 ml) was added a solution of 19% (W/V) hydrogen chloride in methanol (31.6 ml) and the mixture was stirred for an hour at ambient temperature. To a reaction mixture was added a isopropyl ether and the isolated precipitate was collected by filtration. The precipitate was recrystallized from an aqueous ethanol to give 2-(diaminomethyleneamino)-4-(5-ureidomethylfuran-2-yl)thiazole hydrochloride (6.82 g).

Provenance & Evidence