Oxalyl chloride → 4,4,4-Trifluorobutanoyl chloride

HRID 1033201Notes

Reaction equation

HRID 1033201 reaction equation
[F:1][C:2]([F:9])([F:8])[CH2:3][CH2:4][C:5](O)=[O:6].C(Cl)(=O)C([Cl:13])=O>C1C=CC=CC=1>[F:1][C:2]([F:9])([F:8])[CH2:3][CH2:4][C:5]([Cl:13])=[O:6]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 27770854,4,4-Trifluorobutanoic acid

Product 1

HCID 151044744,4,4-Trifluorobutanoyl chloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

4,4,4-Trifluorobutyric acid (5.8 g, 0.041 mole) was dissolved in benzene (30 ml). Oxalyl chloride (6.2 g, 0.049 mole) was added and the reaction stirred for 20 hrs. The benzene and excess oxalyl chloride was removed by distillation to give the title compound.

Workup

  1. customThe benzene and excess oxalyl chloride was removed by distillation

Sources & evidence

ORD record
ord-287de6d0994a477c8b9db3a80ef4bb84
Source dataset
uspto-grants-1994_05
Patent number
US05310745

Reaction notes

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