3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid → HCID 19025547, compound

Participants

Reaction Steps

Prepared from 3-t-butoxycarbonylamino-3-methylbutanoic acid (Example 31, Step E) and the amine obtained in Step D by the procedure described in Example 1, Step F. 1H NMR (200 MHz, CDCl3): 1.32 (s,6H), 1.38 (s,9H), 1.86 (m,1H), 2.4-3.0 (m,5H), 3.77 (s,3H), 4.49 (m,1H), 5.25 9br s,1H), 6.68 (d,8 Hz, 1H), 6.70 (s,1H), 6.89 (d,8 Hz, 1H), 7.55 (br s,1H). FAB-MS: calculated for C21H31N3O5 405; found 428 (m+na,100%), 406 M+H,23%).

Provenance & Evidence