4-Methoxybenzylamine → HCID 18651508, compound

Participants

Reaction Steps

The title compound was prepared from 4'-[[2,3,4,5-tetrahydro-3(R)-[[3-methyl-1-oxo-3-[[(benzyloxyoxy)carbonyl]amino]butyl]amino]-2-oxo-1H-1-benzazepin-1-yl]methyl][1,1'-biphenyl]-2-carboxylic acid (Example 72, Step B) and 4-methoxybenzylamine by the procedure described in Example 74, Step A. 1H NMR (200 MHz,CD3OD) 1.40 (s,6H), 2.00 (m,1H), 2.31 (m,1H), 2.50-2.75 (m,4H), 3.82 (s,3H), 4.27 (s,2H), 4.43 (dd;7,11 Hz;1H), 4.95 (d,15 Hz,1H), 5.05 (d,12 Hz,1H), 5.15 (d,12 Hz,1H), 5.37 (d,15 Hz,1H), 6.87 (m,3H), 7.03 (d,8 Hz,2H), 7.20-7.57 (m,19H). FAB-MS: calculated for C45H46N4O6 738; found 7.40.

Provenance & Evidence