Acetonitrile → 4-[5-[Tert-butyl(dimethyl)silyl]oxypent-3-en-1-ynyl]-6-phenoxypyrimidin-5-amine

HRID 103357Notes

Reaction equation

HRID 103357 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[Si:20]([O:21][CH2:22][CH:23]=[CH:24][C:25]#[CH:26])([CH3:27])[CH3:28].[CH3:29][C:30]#[N:31].[Cu:32][I:33].[I:1][c:2]1[n:3][cH:4][n:5][c:6]([O:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[c:7]1[NH2:8]>>[c:2]1([C:26]#[C:25][CH:24]=[CH:23][CH2:22][O:21][Si:20]([C:16]([CH3:17])([CH3:18])[CH3:19])([CH3:27])[CH3:28])[n:3][cH:4][n:5][c:6]([O:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[c:7]1[NH2:8]

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 71339445tert-Butyl(dimethyl)[(pent-2-en-4-yn-1-yl)oxy]silaneHCID 860847854-Iodo-6-phenoxy-5-pyrimidinamine

Product 1

HCID 914094564-[5-[Tert-butyl(dimethyl)silyl]oxypent-3-en-1-ynyl]-6-phenoxypyrimidin-5-amine

Sources & evidence

ORD record
ord-5b287a3937254a2c94c47a22c1c4c4e8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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