2-Pentynoic acid, methyl ester → HCID 178440058, Verbindung

HRID 1033605Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1033605
[C:1]([O:7][CH3:8])(=[O:6])[C:2]#[C:3][CH2:4][CH3:5].[C:9](=[N:14]O)([NH2:13])[CH2:10][CH2:11][CH3:12]>C1(C)C(C)=CC=CC=1>[CH2:4]([C:3]1[N:13]=[C:9]([CH2:10][CH2:11][CH3:12])[NH:14][C:2]=1[C:1]([O:7][CH3:8])=[O:6])[CH3:5]

Komponenten

4

Edukt 2

HCID 904702-Pentynoic acid, methyl esterHCID 2794811N-Hydroxybutyramidine

Produkt 1

HCID 178440058HCID 178440058, VerbindungAusbeute 27,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7237O-XyleneLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

93 g of methyl pentynoate and 82 g butyramidoxime are mixed together without solvent and heated to 50° C for 24 hours. 400 mL xylene was added and water was azaeotropically removed for 6 hours. The reaction was then distilled (140° C. at 0.2 torr) to give 44 g product.

Aufarbeitung

  1. customwater was azaeotropically removed for 6 hours
  2. distillationThe reaction was then distilled (140° C. at 0.2 torr)

Quellen und Nachweise

ORD-Eintrag
ord-9f5701372eab455db5c3bc9937b31efa
Quelldatensatz
uspto-grants-1994_05
Patentnummer
US05310929

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