Trifluoroacetic acid → HCID 19024453, compound

Participants

Reaction Steps

The title compound was prepared from 1-[N-butyl-N-[[2'-(N-t-butylsulfamoyl)biphenyl-4-yl]methyl]carbamoyl]-1,2,3,4-tetrahydroquinoline (from Step A) and TFA in the presence of anisole, according to the procedure of Example 4, Step B, to give a 97% yield of the desired material after flash chromatography as a foam, homogeneous by TLC in 95:5 CH2Cl2 --MeOH; FAB-MS m/e 478 (M+1)+.

Provenance & Evidence