HCID 19024460, compound → HCID 19024424, compound

Participants

Reaction Steps

The title compound was prepared from 1-butyl-1-[[2'-(N-t-butylsulfamoyl)biphenyl-4-yl]methyl]-3-methyl-3-[2-(trifluoromethyl)phenyl]urea (from Step B) according to the procedure of Example 2, Step D. Purification of the crude product by flash chromatography (elution with 2:1 and then 1:1 hexane-EtOAc) afforded a 76% yield of a stiff, white foam, which became tacky upon standing; homogeneous by TLC (3:1 hexane-EtOAc); FAB-MS m/e 521 (M+1)+.

Provenance & Evidence