反应详情

It is used in the synthesis of MOPMN, above, and was synthesized from 2-bromo-4'-methoxyacetophenone (Aldrich). The 2-bromo-4'-methoxyacetophenone was refluxed in 20% water and N-methyl-2-pyrrolidinone for 10 hours at 105° C. The product was extracted with ethylether, dried over MgSO4, the ether evaporated and the dry solid recrystallized before use. Melting point 98.5°-100.5° C. and the NMR corresponds to the product.

1. customIt is used in the synthesis of MOPMN
2. extractionThe product was extracted with ethylether
3. dry with materialdried over MgSO4
4. customthe ether evaporated
5. customthe dry solid recrystallized before use