Butylamine → HCID 19023630, compound

HRID 1034171Notes

Reaction equation

HRID 1034171 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][S:6]([C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=O)(=[O:8])=[O:7].[CH2:17]([NH2:21])[CH2:18][CH2:19][CH3:20].S([O-])([O-])(=O)=O.[Mg+2]>S(=O)(=O)(O)O.C(OCC)C>[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][S:6]([C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=[N:21][CH2:17][CH2:18][CH2:19][CH3:20])(=[O:8])=[O:7]

Participants

6

Reactant 3

HCID 8007ButylamineHCID 24083Sulfuric acid magnesium salt (1:1)HCID 19023627HCID 19023627, compound

Product 1

HCID 19023630HCID 19023630, compound

Reagents, catalysts & solvents 2

HCID 1118Sulfuric AcidCatalystHCID 3283Diethyl EtherSolvent

Procedure

2.45 g of 2-[(4-chlorobutyl)sulfonyl]benzaldehyde was treated with 1.1 ml of n-butylamine, 3.4 g of magnesium sulfate, and 2 drops of concentrated sulfuric acid in 20 ml of diethyl ether in the same manner as described for Example 1, Part C to give 2.76 g of product. 1H-NMR (CDCl3) δ 0.96(t,3H,J=7 Hz); 1.32-1.50(m,2H); 1.65-1.79(m,2H); 1.84-1.93(m,4H); 3.11-3.20(m,2H); 3.46-3.53(m,2H); 3.67-3.74(m,2H); 7.55-7.73(m,2H); 8.00-8.13(m,2H); 9.12(s,1H).

Sources & evidence

ORD record
ord-f0ac60b25bba4e629a27058c8a505e19
Source dataset
uspto-grants-1994_05
Patent number
US05314887

Reaction notes

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