Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isobutyl chloroformate → 1-(1,4-Dioxaspiro[4.5]dec-7-ylcarbonyl)-4-(2-pyridinyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isobutyl chloroformate | HCID 62365 | — |
| 반응물 | 1-(2-Pyridyl)piperazine | HCID 94459 | — |
| 반응물 | 1,4-Dioxaspiro[4.5]decane-7-carboxylic acid | HCID 567492 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | 1-(1,4-Dioxaspiro[4.5]dec-7-ylcarbonyl)-4-(2-pyridinyl)piperazine | HCID 20076682 | 58.2% |
반응 단계
From 1,4-dioxaspiro[4.5]decane-7-carboxylic acid (Example A, Step A) (10 g), triethylamine (8 g), isobutyl chloroformate (7.9 g) and 1-(2-pyridyl)piperazine (8.3 g) using the procedure of Example A, Step B is obtained 9.8 g of the title compound as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05314896 |
| 출처 데이터셋 | uspto-grants-1994_05 |
| ORD ID | ord-57082393d93048c79044a7aed3e29764 |
| 출처 메모 | uspto-grants-1994_05 |