HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminum(III) Chloride → 1-(1,4-Dioxaspiro[4.5]dec-7-ylmethyl)-4-(2-pyridinyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 1-(1,4-Dioxaspiro[4.5]dec-7-ylcarbonyl)-4-(2-pyridinyl)piperazine | HCID 20076682 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | 1-(1,4-Dioxaspiro[4.5]dec-7-ylmethyl)-4-(2-pyridinyl)piperazine | HCID 20076702 | 92.6% |
Reaction Steps
From aluminum chloride (5.39 g), lithium aluminum hydride (4.61 g) and 1-(1,4-dioxaspiro[4.5]dec-7-ylcarbonyl)-4-(2-pyridinyl)piperazine (40.22 g) (Step A) using the procedure of Example A, Step C is obtained 35.66 g of the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05314896 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-2408833dcde241049d8f6e7c6bf5d311 |
| Source note | uspto-grants-1994_05 |