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HRID1034283

反应详情

EQUATION

反应方程式

HRID 1034283 的结构方程式

REACTANTS

反应物

3
结构：CCOC(=O)c1ccc(C)cc1
HCID66743

Ethyl 4-methylbenzoate

C10H12O2

结构：O=C1CCC(=O)N1Br
HCID67184

1-Bromopyrrolidine-2,5-dione

C4H4BrNO2

结构：Cc1ccc(S(=O)(=O)N(C)C2CCCCC2)cc1
HCID614169

N-Cyclohexyl-N,4-dimethylbenzenesulfonamide

C14H21NO2S

PRODUCTS

生成物

1
结构：CN(C1CCCCC1)S(=O)(=O)c1ccc(CBr)cc1
HCID19023272

未命名化合物

收率 90.1%

PROCEDURE

实验过程

Utilising the procedure described in Example 1(a) employing N-cyclohexyl-N-methyl 4-methylbenzenesulphonamide (20.0 g, 0.075 mol) in lieu of ethyl 4-methylbenzoate and two equivalents of NBS (27.0 g, 0.15 mol) yielded a crude product of N-cyclohexyl-N-methyl 4-bromomethylbenzenesulphonamide (23.4 g, 90%) as an orange oil.