HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (S)-5-Methyl-3-nitromethyl-hexanoic acid monopotassium salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Chloride | HCID 4873 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | (S)-5-methyl-3-nitromethyl-hexanoic acid ethyl ester | HCID 29984078 | — |
| Solvent | Water | HCID 962 | — |
| Product | (S)-5-Methyl-3-nitromethyl-hexanoic acid monopotassium salt | HCID 87239685 | — |
Reaction Steps
830 mg of (S)-5-methyl-3-nitromethyl-hexanoic acid ethyl ester (VIII, R1=ethyl) were suspended in 0.8 mL of H2O. 900 mg of 50% aqueous KOH were added. After 5 h at 25° C. conversion was complete (determination by HPLC). 4.2 mL of 1M aqueous HCl were added and the solvent was removed under reduced pressure to give a solid consisting of the title compound and KCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546112B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-b7eda5d63df049cc95cd00179f98041d |
| Source note | uspto-grants-2013_10 |