4-(Azidomethyl)-3-fluoropyridine → 1-(3-Fluoropyridin-4-yl)methanamine
Reaction equation
[N:1]([CH2:4][C:5]1[CH:10]=[CH:9][N:8]=[CH:7][C:6]=1[F:11])=[N+]=[N-]>[Pt]>[F:11][C:6]1[CH:7]=[N:8][CH:9]=[CH:10][C:5]=1[CH2:4][NH2:1]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The product of Example 129C was processed according to the method of Example 115B except that Pt/C was used instead of Pd/C as catalyst. MS (ESI+) m/z 127 (M+H)+;
Sources & evidence
- ORD record
- ord-b95041ea78ea4a0a83081c78a35db7e0
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08546374B2
Reaction notes
Loading…