HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-2-naphthalenol → 6-Phenylnaphthalen-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-2-naphthalenol | HCID 27144 | — |
| Reactant | Phenyl dihydrogen orthoborate | HCID 78412 | — |
| Product | 6-Phenylnaphthalen-2-ol | HCID 10125182 | 87% |
Reaction Steps
The compound is prepared by the reaction of 6-bromo-2-naphthol (500 mg, 2.24 mmol, 1 eq) with phenylboric acid (1 eq) according to method A within 20 h. Purification by column chromatography with hexane/ethyl acetate 7/3 as the eluent yields the desired product in a yield of 87%, 429 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546392B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-5424f8bc91594aac919514a62e3cbcc2 |
| Source note | uspto-grants-2013_10 |