Boron tribromide → HCID 25074167, compound

HRID 1035674Notes

Reaction equation

HRID 1035674 reaction equation
C[O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19]C)[CH:14]=3)[CH:9]=2)[C:4]=1[C:21]1[CH:22]=[C:23]([NH2:27])[CH:24]=[CH:25][CH:26]=1.B(Br)(Br)Br>>[NH2:27][C:23]1[CH:22]=[C:21]([C:4]2[C:5]3[C:10](=[CH:9][C:8]([C:13]4[CH:18]=[CH:17][CH:16]=[C:15]([OH:19])[CH:14]=4)=[CH:7][CH:6]=3)[CH:11]=[CH:12][C:3]=2[OH:2])[CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 50942707HCID 50942707, compound

Product 1

HCID 25074167HCID 25074167, compound

Procedure

The compound is prepared by the reaction of 3-(2-methoxy-6-(3-methoxyphenyl)naphthalene-1-yl)benzeneamine (1 g, 2.82 mmol, 1 eq) with boron tribromide solution (14.1 ml, 14.1 mmol, 5 eq) according to method G. Purification by column chromatography was not necessary, and the desired product was obtained in quantitative yield (922 mg) after processing.

Workup

  1. customPurification by column chromatography

Sources & evidence

ORD record
ord-cb78ca08082f411b958f7569a3ea1d0b
Source dataset
uspto-grants-2013_10
Patent number
US08546392B2

Reaction notes

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