HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Nitro-4-(piperidin-4-ylamino)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67126453 | HCID 67126453 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Nitro-4-(piperidin-4-ylamino)benzenesulfonamide | HCID 43345806 | — |
Reaction Steps
Tert-butyl 4-(2-nitro-4-sulfamoylphenylamino)piperidine-1-carboxylate was dissolved in dichloromethane (3 mL) and treated with 1N HCl in ether (4 mL). The reaction was stirred overnight then concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546399B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-7afd8d7da9a74f74adca6ddf5f88d4e4 |
| Source note | uspto-grants-2013_10 |