Hydrochloric Acid → HCID 67126662, compound
Reaction equation
[F:1][CH2:2][CH:3]([N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH:13]C(=O)OC(C)(C)C)[CH2:7]1)[CH2:4][F:5].Cl>O1CCOCC1>[F:5][CH2:4][CH:3]([N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH2:13])[CH2:7]1)[CH2:2][F:1]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of EXAMPLE 252A (538 mg) in dioxane (4 mL) was treated with 4.0M HCl in dioxane solution (1.8 mL). The reaction was stirred at room temperature overnight. The reaction mixture was concentrated under vacuum and used without further purification.
Workup
- concentrationThe reaction mixture was concentrated under vacuum
- customused without further purification
Sources & evidence
- ORD record
- ord-b17f2de9a380401082d55f78b9fe899c
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08546399B2
Reaction notes
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