HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 71060422, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 71060151 | HCID 71060151 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 71060422 | HCID 71060422 | — |
Reaction Steps
Tert-butyl 1-oxo-4-phenyl-2-(2,2,2-trifluoroethyl)-2,7-diazaspiro[4.5]decane-7-carboxylate (0.874 g, 2.119 mmol) in DCM (10 ml) was treated with 4M HCl in 1,4-dioxane (4.5 ml, 0.018 mmol). The reaction mixture was stirred at room temperature for 9 hours. The solvent was removed in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546416B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-feb523d4a1c549eea3a829857bb2f85b |
| Source note | uspto-grants-2013_10 |