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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1036728Generated: October 30, 2026

Hydrochloric Acid → HCID 71060422, compound

https://huagongshe.com/reaction/1036728

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 71060151HCID 71060151—
SolventDichloromethaneHCID 6344—
ProductHCID 71060422HCID 71060422—

Reaction Steps

Tert-butyl 1-oxo-4-phenyl-2-(2,2,2-trifluoroethyl)-2,7-diazaspiro[4.5]decane-7-carboxylate (0.874 g, 2.119 mmol) in DCM (10 ml) was treated with 4M HCl in 1,4-dioxane (4.5 ml, 0.018 mmol). The reaction mixture was stirred at room temperature for 9 hours. The solvent was removed in vacuo to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546416B2
Source datasetuspto-grants-2013_10
ORD IDord-feb523d4a1c549eea3a829857bb2f85b
Source noteuspto-grants-2013_10