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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1036987Generated: November 1, 2026

Ethyl 4,5-dibromothiophene-2-carboxylate → Ethyl 4-bromo-5-(3-chlorophenyl)thiophene-2-carboxylate

https://huagongshe.com/reaction/1036987

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4,5-dibromothiophene-2-carboxylateHCID 15073982—
ReactantEthyl 4-bromo-5-(3-chloro-5-fluorophenyl)thiophene-2-carboxylateHCID 58066756—
ProductEthyl 4-bromo-5-(3-chlorophenyl)thiophene-2-carboxylateHCID 58066739—

Reaction Steps

The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 9A starting with the compound from Example 8A. 125 mg (57% of theory) of the title compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546438B2
Source datasetuspto-grants-2013_10
ORD IDord-7f1c8a2e60684095a4b6c4cb14060a1f
Source noteuspto-grants-2013_10