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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1036996Generated: November 2, 2026

Ethyl 4-bromo-5-(3-chlorophenyl)thiophene-2-carboxylate → 4-Bromo-5-(3-chlorophenyl)thiophene-2-carboxylic acid

https://huagongshe.com/reaction/1036996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-bromo-5-(3-chlorophenyl)thiophene-2-carboxylateHCID 58066739—
Reactant5-(3-Chloro-5-fluorophenyl)-4-(3-cyanophenyl)thiophene-2-carboxylic acidHCID 58066757—
Product4-Bromo-5-(3-chlorophenyl)thiophene-2-carboxylic acidHCID 58066748—

Reaction Steps

The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 19A starting with the compound from Example 10A. 1.11 g (100% of theory) of the title compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546438B2
Source datasetuspto-grants-2013_10
ORD IDord-4bc8664ec83249ce892fef9ccf5745e9
Source noteuspto-grants-2013_10