3-{2-(3-Chloro-5-fluorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]thiophen-3-yl}benzenecarbonitrile → 1-{[4-(3-Chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)thiophen-2-yl]carbonyl}imidazolidin-4-one

Participants

Reaction Steps

The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 1 starting with 49.1 mg (0.13 mmol) of the compound from Example 20A. 40.9 mg (71% of theory) of the title compound are obtained.

Provenance & Evidence