HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-6-methoxybenzaldehyde → 1-(2-Fluoro-6-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-6-methoxybenzaldehyde | HCID 2737357 | — |
| Reactant | 1-(5-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067672 | — |
| Product | 1-(2-Fluoro-6-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067629 | 77% |
Reaction Steps
Following the procedure used to prepare 1-(5-fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol, 2-fluoro-6-methoxy-benzaldehyde (947 mg, 6.14 mmol) was reacted to give the title compound (1.21 g, 77%). 1H NMR (400 MHz, DMSO-d6): δ 7.41-7.30 (m, 6H), 6.91-6.79 (m, 2H), 5.97-5.94 (m, 1H), 5.90-5.87 (d, 1H), 3.86 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-4b36a16ec3a24b37a19c6178548755ed |
| Source note | uspto-grants-2013_10 |