HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15152169, compound → HCID 67067797, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15152169 | HCID 15152169 | — |
| Reactant | {1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester | HCID 67067635 | — |
| Product | HCID 67067797 | HCID 67067797 | 44% |
Reaction Steps
Following the procedure used to prepare {1-[4-(6-fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester, 3-iodo-6-methoxy-2-phenyl-chromen-4-one (76 mg, 0.20 mmol) was reacted to give the title compound (42 mg, 44%). 1H NMR (400 MHz, CDCl3): δ 7.68-7.64 (d, 1H), 7.51-7.16 (m, 11H), 5.05 (s, 1H), 3.92 (s, 3H), 2.61-2.45 (m, 4H), 2.16-1.75 (m, 2H), 1.52-1.00 (m, 9H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-d6aca42f0f98494ca0d4b63de4f19595 |
| Source note | uspto-grants-2013_10 |