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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037166Generated: October 30, 2026

HCID 15152169, compound → HCID 67067797, compound

https://huagongshe.com/reaction/1037166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 15152169HCID 15152169—
Reactant{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl esterHCID 67067635—
ProductHCID 67067797HCID 6706779744%

Reaction Steps

Following the procedure used to prepare {1-[4-(6-fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester, 3-iodo-6-methoxy-2-phenyl-chromen-4-one (76 mg, 0.20 mmol) was reacted to give the title compound (42 mg, 44%). 1H NMR (400 MHz, CDCl3): δ 7.68-7.64 (d, 1H), 7.51-7.16 (m, 11H), 5.05 (s, 1H), 3.92 (s, 3H), 2.61-2.45 (m, 4H), 2.16-1.75 (m, 2H), 1.52-1.00 (m, 9H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546376B2
Source datasetuspto-grants-2013_10
ORD IDord-d6aca42f0f98494ca0d4b63de4f19595
Source noteuspto-grants-2013_10