HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-5-(trifluoromethoxy)benzaldehyde → 1-(2-Methoxy-5-trifluoromethoxy-phenyl)-3-phenyl-prop-2-yn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-5-(trifluoromethoxy)benzaldehyde | HCID 2783364 | — |
| Reactant | 1-(5-Fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067672 | — |
| Product | 1-(2-Methoxy-5-trifluoromethoxy-phenyl)-3-phenyl-prop-2-yn-1-ol | HCID 67067693 | 99% |
Reaction Steps
Following the procedure used to prepare 1-(5-fluoro-2-methoxy-phenyl)-3-phenyl-prop-2-yn-1-ol, 2-methoxy-5-trifluoromethoxy-benzaldehyde was reacted to give the title compound as a pale yellow oil (642 mg, 99%). LCMS (Method B): RT=4.55 min, [M−H2O+H]+=305.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-b4a2a4d7b51b45069a1324e025fb7808 |
| Source note | uspto-grants-2013_10 |