HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3-methoxypyridine-4-carbaldehyde → 1-(2-Chloro-3-methoxy-pyridin-4-yl)-3-phenyl-prop-2-yn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3-methoxypyridine-4-carbaldehyde | HCID 59727740 | — |
| Reactant | 1-(2,6-Dimethoxy-pyridin-3-yl)-3-phenyl-prop-2-yn-1-ol | HCID 67067816 | — |
| Product | 1-(2-Chloro-3-methoxy-pyridin-4-yl)-3-phenyl-prop-2-yn-1-ol | HCID 86671030 | 100% |
Reaction Steps
Following the procedure used to prepare 1-(2,6-dimethoxy-pyridin-3-yl)-3-phenyl-prop-2-yn-1-ol, 2-chloro-3-methoxy-pyridine-4-carbaldehyde was reacted to give the title compound (1.60 g, 100%) as a colourless solid, LCMS (Method A): RT=4.14 min, [M+H]+=274/276.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546376B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-c11d342059f74501a2ad132532ca7d68 |
| Source note | uspto-grants-2013_10 |