HRID1037313

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11523469

6-FLUORO-3-IODO-2-PHENYLCHROMEN-4-ONE

C15H8FIO2

结构：COc1c(C(=O)C#Cc2ccccc2)ccn2c(=O)n(COCC[Si](C)(C)C)nc12

HCID67067859

未命名化合物

PRODUCTS

生成物

结构：C[Si](C)(C)CCOCn1nc2c3oc(-c4ccccc4)c(I)c(=O)c3ccn2c1=O

HCID86671039

未命名化合物

收率 81%

PROCEDURE

实验过程

Following the procedure used to prepare 6-fluoro-3-iodo-2-phenyl-chromen-4-one, 8-methoxy-7-(3-phenyl-propynoyl)-2-(2-trimethylsilanyl-ethoxymethyl)-2H-[1,2,4]triazolo[4,3-a]pyridin-3-one was reacted to give the title compound as a cream solid (958 mg, 81%). LCMS (Method A): RT=4.80 min, [M+H]+=536.

WORKUP

后处理

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