HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-fluoroaniline → HCID 56963170, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-fluoroaniline | HCID 821848 | — |
| Reactant | 2-(4-chlorophenyl)-5-cyclopropyl-N-methyl-6-[(methylsulfonyl)amino]-2H-indazole-3-carboxamide | HCID 56963169 | — |
| Product | HCID 56963170 | HCID 56963170 | — |
Reaction Steps
Compound (46) was prepared in a similar manner to the synthesis of Compound (44) with the following variation: 4-bromo-3-fluoroaniline was used instead of 4-chloroaniline at Step d. ESI-MS m/z [M+H]+: 481.1. 1H NMR (400 MHz, DMSO) δ 9.21 (brs, 1H), 8.67 (brs, 1H), 7.96-7.83 (m, 2H), 7.76-7.62 (m, 2H), 7.45-7.30 (m, 2H), 3.10 (s, 3H), 2.90-2.76 (m, 3H), 2.31-2.20 (m, 1H), 1.07-0.92 (m, 2H), 0.80-0.66 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546389B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-4f1fa000e8b54ac38e63d172655c2bfb |
| Source note | uspto-grants-2013_10 |