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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1037611Generated: November 1, 2026

HCID 86627645, compound → HCID 86627646, compound

https://huagongshe.com/reaction/1037611

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86627645HCID 86627645—
SolventMethanolHCID 887—
ProductHCID 86627646HCID 8662764699.9%

Reaction Steps

Crude 4-{5-chloro-2-[(2-chloro-pyridine-4-carbonyl)-amino]phenyl}-3,6-dihydro-2H-pyridine-1-carboxylic acid 1-chloro-ethyl ester (550 mg) was dissolved in methanol (25 ml) in and heated to reflux for 16 hours. Evaporation afforded the crude title product (465 mg). Retention Time HPLC 1.48 min; MS (ES+) 350, 348 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546569B2
Source datasetuspto-grants-2013_10
ORD IDord-85987eeeb8e242d6baf874b64db82002
Source noteuspto-grants-2013_10