反应详情

1.05 g of 2-bromo-4,5-difluorobenzoyl chloride in 5 ml of DCM are added dropwise with stirring to a solution of 846.9 μl of diethylamine in 5 ml of DCM. The mixture is subsequently stirred at RT for 1 h. The mixture is then extracted a number of times against water (pH 9), the organic phase is dried and purified by column chromatography.

1. extractionThe mixture is then extracted a number of times against water (pH 9)
2. customthe organic phase is dried
3. custompurified by column chromatography