Hydrochloric Acid → 5-fluoro-N-{3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl}quinazolin-4-amine
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][c:10]1[cH:11][n:12][c:13]([CH3:16])[cH:14][cH:15]1.[CH3:36][C:37]#[N:38].[Cl:24][c:25]1[n:26][cH:27][n:28][c:29]2[cH:30][cH:31][cH:32][c:33]([F:35])[c:34]12.[ClH:17].[O:18]1[CH2:19][CH2:20][O:21][CH2:22][CH2:23]1>>[CH3:1][c:2]1[cH:3][c:4]([NH:5][c:25]2[n:26][cH:27][n:28][c:29]3[cH:30][cH:31][cH:32][c:33]([F:35])[c:34]23)[cH:6][cH:7][c:8]1[O:9][c:10]1[cH:11][n:12][c:13]([CH3:16])[cH:14][cH:15]1Participants
6
Sources & evidence
- ORD record
- ord-eab57afbfe174a948ff38f69257c9570
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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