Allyl bromide → 3-allyl-5-methylthiazol-2(3H)-imine hydrobromide

HRID 1037911Notes

Reaction equation

[NH2:1][C:2]1[S:3][C:4]([CH3:7])=[CH:5][N:6]=1.[CH2:8]([Br:11])[CH:9]=[CH2:10]>>[BrH:11].[CH2:10]([N:6]1[CH:5]=[C:4]([CH3:7])[S:3][C:2]1=[NH:1])[CH:9]=[CH2:8]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 3517702-Amino-5-methylthiazole

Product 1

HCID 686217733-allyl-5-methylthiazol-2(3H)-imine hydrobromide

Procedure

A mixture of 2-amino-5-methylthiazole (2.5 g) and allylbromide (3.31 g) was processed according to the method of Example 227A to afford the title compound that was taken directly to the next step. MS (ESI+) m/z 155 (M+H)+.

Sources & evidence

ORD record: ord-0246485785de45bfad61e1a05e53d620
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08546583B2

Reaction notes

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