HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazole, 3-(4-morpholinyl)-5-nitro- → 3-Morpholino-1H-indazol-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazole, 3-(4-morpholinyl)-5-nitro- | HCID 3051326 | — |
| Catalyst | HCID 178418361 | HCID 178418361 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Morpholino-1H-indazol-5-amine | HCID 3079858 | — |
Reaction Steps
3-Morpholin-4-yl-5-nitro-1H-indazole (210 mg) was dissolved in 10 ml of methanol and the mixture hydrogenated at 1 atm of hydrogen using 10% Pd/C (50 mg) as catalyst. After 24 hrs, the mixture was filtered and evaporated for use in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546404B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-cae09478cbda4e4582b5f19178b28be9 |
| Source note | uspto-grants-2013_10 |