化工社化工社 化学情報印刷レポート · 研究参考用
N-methyl-5-nitro-1H-indazole-3-carboxamide → 5-Amino-N-methyl-1H-indazole-3-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-methyl-5-nitro-1H-indazole-3-carboxamide | HCID 45810073 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 5-Amino-N-methyl-1H-indazole-3-carboxamide | HCID 22567319 | 105.1% |
反応手順
To a suspension of compound 55 (65 mg) in 5 mL of methanol was added catalytic amount of 5% palladium on carbon. The mixture was stirred under a hydrogen atmosphere at room temperature for 4 hrs and filtered through celite. The filtrate was concentrated to afford compound 56 (59 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08546404B2 |
| 出典データセット | uspto-grants-2013_10 |
| ORD ID | ord-7008f161220d40e19af52abfa231e6b5 |
| 出典メモ | uspto-grants-2013_10 |