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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038042Generated: October 31, 2026

Trifluoroacetic acid → 4-(Phenylethynyl)piperidine

https://huagongshe.com/reaction/1038042

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantN-BOC-4-(phenylethynyl)piperidineHCID 17986993—
Product4-(Phenylethynyl)piperidineHCID 17986965—

Reaction Steps

4-Phenylethynyl-piperidine-1-carboxylic acid tert-butyl ester was treated with TFA for 10 minutes and concentrated, lyophilized to provide the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546404B2
Source datasetuspto-grants-2013_10
ORD IDord-0e507e666e7f493f85b4c3610235c6ba
Source noteuspto-grants-2013_10