HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene methanol → 3-(2-Cyclopropyl-pyridin-4-yl)-1-trityl-1H-indazol-5-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene methanol | HCID 21867641 | — |
| Reactant | 3-(2-Cyclopropyl-pyridin-4-yl)-5-nitro-1-trityl-1H-indazole | HCID 57686276 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 3-(2-Cyclopropyl-pyridin-4-yl)-1-trityl-1H-indazol-5-ylamine | HCID 57685838 | — |
Reaction Steps
3-(2-Cyclopropyl-pyridin-4-yl)-5-nitro-1-trityl-1H-indazole (2 gm) was dissolved in 20 mol of 50% methanol/toluene and balloon hydrogenated for 18 hrs in the presence of 0.4 gm of 50% by weight 10% Pd/C. The reaction mixture was filtered and evaporated to give the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546404B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-05f188df39214e9698fe4f453bb0e209 |
| Source note | uspto-grants-2013_10 |