HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 71046973, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Bicarbonate | HCID 516893 | — |
| Reactant | HCID 57686028 | HCID 57686028 | — |
| Reactant | HCID 86630176 | HCID 86630176 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 71046973 | HCID 71046973 | — |
Reaction Steps
Pyrrolidine-3-carboxylic acid [3-(4-fluoro-phenyl)-1H-indazol-5-yl]-amide (24AB) (30 mg, 0.093 mmol, 1 equiv), 2-Chloro-1-{4-[3-fluoro-4-(5-fluoro-pyrimidin-2-yl)-phenyl]-3,6-dihydro-2H-pyridin-1-yl}-ethanone (23AB) (36 mg, 0.102 mmol, 1.1 equiv), potassium bicarbonate (47 mg, 0.465 mmol, 5 equiv), and sodium iodide (3 mg, 0.019 mmol, 0.2 equiv) were all weighed out in a flask and to it was added acetonitrile (3 mL). The reaction content was stirred at room temperature overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08546404B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-c61192dd617041f7b607eb4824f21669 |
| Source note | uspto-grants-2013_10 |