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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038113Generated: October 28, 2026

Sodium Iodide → HCID 71046973, compound

https://huagongshe.com/reaction/1038113

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantPotassium BicarbonateHCID 516893—
ReactantHCID 57686028HCID 57686028—
ReactantHCID 86630176HCID 86630176—
SolventAcetonitrileHCID 6342—
ProductHCID 71046973HCID 71046973—

Reaction Steps

Pyrrolidine-3-carboxylic acid [3-(4-fluoro-phenyl)-1H-indazol-5-yl]-amide (24AB) (30 mg, 0.093 mmol, 1 equiv), 2-Chloro-1-{4-[3-fluoro-4-(5-fluoro-pyrimidin-2-yl)-phenyl]-3,6-dihydro-2H-pyridin-1-yl}-ethanone (23AB) (36 mg, 0.102 mmol, 1.1 equiv), potassium bicarbonate (47 mg, 0.465 mmol, 5 equiv), and sodium iodide (3 mg, 0.019 mmol, 0.2 equiv) were all weighed out in a flask and to it was added acetonitrile (3 mL). The reaction content was stirred at room temperature overnight.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546404B2
Source datasetuspto-grants-2013_10
ORD IDord-c61192dd617041f7b607eb4824f21669
Source noteuspto-grants-2013_10