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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1038114Generated: November 3, 2026

Triethylamine → HCID 86630177, compound

https://huagongshe.com/reaction/1038114

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantHCID 57686028HCID 57686028—
ReactantHCID 86630178HCID 86630178—
SolventDimethylformamideHCID 6228—
ProductHCID 86630177HCID 86630177—

Reaction Steps

3-Methoxymethyl-pyrrolidine-3-carboxylic acid [3-(2-cyclopropyl-pyridin-4-yl)-1H-indazol-5-yl]-amide (26AB) (85 mg, 0.217 mmol, 1 equiv) and 2-Chloro-1-{4-[3-fluoro-4-(5-fluoro-pyrimidin-2-yl)-phenyl]-3,6-dihydro-2H-pyridin-1-yl}-ethanone (23AB) (84 mg, 0.239 mmol, 1.1 equiv) were weighed out in a flask and dissolved in anhydrous N,N-dimethylformamide (5 mL). Triethyl amine (33 mg, 46 uL, 0.326 mmol, 1.5 equiv) was added to the reaction mixture and the reaction content was stirred at room temperature overnight.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08546404B2
Source datasetuspto-grants-2013_10
ORD IDord-199f5d0e518049cb95cd904b470d3e6c
Source noteuspto-grants-2013_10